help  | about  | cite  | software

Gene : QARS1 Homo sapiens

Name  ? glutaminyl-tRNA synthetase 1 Cytological Location  3p21.31
Brief Description  glutaminyl-tRNA synthetase 1
Description  Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • synonyms:
  • QARS,
  • NM_005051,
  • uc003cvx.6,
  • glutaminyl-tRNA synthetase,
  • glutamine tRNA ligase,
  • QARS1,
  • OTTHUMG00000156774,
  • GLNRS,
  • PRO2195,
  • MSCCA,
  • HGNC:9751,
  • QARS,
  • X76013
  • identifiers:
  • 5859,
  • ENSG00000172053,
  • QARS1

Genome feature

Region: gene ? Length: 8827  
Location: 3:49095932-49104758 reverse strand Cyto location: 3p21.31


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

27 SN Ps

4 Cross References

19 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results