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Gene : BCHE Homo sapiens

Name  ? butyrylcholinesterase Cytological Location  3q26.1
Brief Description  butyrylcholinesterase
Description  This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine. [provided by RefSeq, Jul 2016]
  • synonyms:
  • CHE2,
  • CHE2,
  • BCHE,
  • uc003fem.5,
  • cholinesterase (serum) 2,
  • E1,
  • BCHED,
  • M16541,
  • OTTHUMG00000158131,
  • HGNC:983,
  • NM_000055,
  • CHE1,
  • cholinesterase 1,
  • CHE1,
  • E1
  • identifiers:
  • 590,
  • ENSG00000114200,
  • BCHE

Genome feature

Region: gene ? Length: 64520  
Location: 3:165772904-165837423 reverse strand Cyto location: 3q26.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3753 SN Ps

5 Cross References

16 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results