help  | about  | cite  | software

Gene : ACE2 Homo sapiens

Name  ? angiotensin I converting enzyme 2 Cytological Location  Xp22.2
Brief Description  angiotensin I converting enzyme 2
description  The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AF291820,
  • HGNC:13557,
  • OTTHUMG00000021177,
  • peptidyl-dipeptidase A,
  • ACE2,
  • uc004cxb.2,
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 2,
  • ACEH,
  • NM_001371415
  • identifiers:
  • 59272,
  • ENSG00000130234,
  • ACE2

Genome feature

Region: gene ? Length: 107639  
Location: X:15494520-15602158 reverse strand Cyto location: Xp22.2

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3756 SN Ps

5 Cross References

16 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results