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Gene : BCL6 Homo sapiens

Name  ? BCL6 transcription repressor Cytological Location  3q27.3
Brief Description  BCL6 transcription repressor
Description  The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
  • synonyms:
  • ZBTB27,
  • NM_001706,
  • B cell CLL/lymphoma 6,
  • ZNF51,
  • BCL6, transcription repressor,
  • BCL6,
  • BCL5,
  • LAZ3,
  • zinc finger protein 51,
  • uc003frq.3,
  • BCL6A,
  • ZBTB27,
  • BCL5,
  • BCL6A,
  • ZNF51,
  • HGNC:1001,
  • LAZ3,
  • OTTHUMG00000156441
  • identifiers:
  • 604,
  • ENSG00000113916,
  • BCL6

Genome feature

Region: gene ? Length: 24096  
Location: 3:187721377-187745472 reverse strand Cyto location: 3q27.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

65 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results