help  | about  | cite  | software

Gene : BRD2 Homo sapiens

Name  ? bromodomain containing 2 Cytological Location  6p21.32
Brief Description  bromodomain containing 2
Description  This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
  • synonyms:
  • RING3,
  • FSRG1,
  • BRD2-IT1,
  • FSRG1,
  • KIAA9001,
  • RNF3,
  • D6S113E,
  • HGNC:1103,
  • D6S113E,
  • FSH,
  • bromodomain-containing 2,
  • BRD2 intronic transcript 1,
  • O27.1.1,
  • OTTHUMG00000031241,
  • RING3,
  • NAT,
  • uc003ocn.4,
  • BRD2-IT1,
  • NAT,
  • NM_001113182,
  • BRD2,
  • X96670
  • identifiers:
  • 6046,
  • ENSG00000204256,
  • BRD2

Genome feature

Region: gene ? Length: 12912  
Location: 6:32968594-32981505 Cyto location: 6p21.32


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3753 SN Ps

5 Cross References

15 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results