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Gene : ELAC2 Homo sapiens

Name  ? elaC ribonuclease Z 2 Cytological Location  17p12
Brief Description  elaC ribonuclease Z 2
Description  The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • synonyms:
  • uc002gnz.5,
  • elaC homolog 2 (E. coli),
  • AF304370,
  • HPC2,
  • elaC (E. coli) homolog 2,
  • FLJ10530,
  • HGNC:14198,
  • tRNase Z (long form),
  • NM_001165962,
  • ELC2,
  • ELAC2,
  • COXPD17,
  • OTTHUMG00000058764,
  • HPC2
  • identifiers:
  • 60528,
  • ENSG00000006744,
  • ELAC2

Genome feature

Region: gene ? Length: 26453  
Location: 17:12991612-13018064 reverse strand Cyto location: 17p12

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2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

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Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results