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Gene : ABCE1 Homo sapiens

Name  ? ATP binding cassette subfamily E member 1 Cytological Location  4q31.21
Brief Description  ATP binding cassette subfamily E member 1
Description  The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • RNase L inhibitor 1,
  • ATP-binding cassette, sub-family E (OABP), member 1,
  • RLI1,
  • OABP,
  • NM_002940,
  • RNASEL1,
  • HGNC:69,
  • RNS4I,
  • OTTHUMG00000161478,
  • ABCE1,
  • RNASEL1,
  • OABP,
  • ABC38,
  • RLI1,
  • RNS4I,
  • RLI,
  • uc003ijy.4,
  • RNASELI,
  • X74987,
  • RNASELI,
  • RLI
  • identifiers:
  • 6059,
  • ENSG00000164163,
  • ABCE1

Genome feature

Region: gene ? Length: 31214  
Location: 4:145098311-145129524 Cyto location: 4q31.21


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

45 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results