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Gene : BDKRB1 Homo sapiens

Name  ? bradykinin receptor B1 Cytological Location  14q32.2
Brief Description  bradykinin receptor B1
Description  Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  • synonyms:
  • B1BKR,
  • BDKRB1,
  • NM_000710,
  • BDKRB2,
  • B1R,
  • BKB1R,
  • HGNC:1029,
  • BRADYB1,
  • BKR1,
  • OTTHUMG00000171412,
  • bradyb1,
  • BKR1,
  • B1BKR,
  • uc001yfh.4,
  • L42383
  • identifiers:
  • 623,
  • ENSG00000100739,
  • BDKRB1

Genome feature

Region: gene ? Length: 8554  
Location: 14:96256210-96264763 Cyto location: 14q32.2


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Disease

0 Diseases

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Other

302 SN Ps

4 Cross References

15 Data Sets

21 Homologues

0 Located Features

97 Rna Seq Results