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Gene : BGN Homo sapiens

Name  ? biglycan Cytological Location  Xq28
Brief Description  biglycan
Description  This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015]
  • synonyms:
  • SEMDX,
  • NM_001711,
  • uc004fhr.3,
  • SLRR1A,
  • MRLS,
  • BGN,
  • SLRR1A,
  • AK092954,
  • biglycan proteoglycan,
  • PGI,
  • DSPG1,
  • PG-S1,
  • HGNC:1044,
  • DSPG1,
  • OTTHUMG00000024205
  • identifiers:
  • 633,
  • ENSG00000182492,
  • BGN

Genome feature

Region: gene ? Length: 14567  
Location: X:153494980-153509546 Cyto location: Xq28

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



157 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results