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Gene : CCL8 Homo sapiens

Name  ? C-C motif chemokine ligand 8 Cytological Location  17q12
Brief Description  C-C motif chemokine ligand 8
Description  This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014]
  • synonyms:
  • MCP-2,
  • SCYA10,
  • NM_005623,
  • small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2),
  • CCL8,
  • OTTHUMG00000132883,
  • MCP-2,
  • HGNC:10635,
  • X99886,
  • HC14,
  • chemokine (C-C motif) ligand 8,
  • HC14,
  • SCYA8,
  • MCP2,
  • uc002hib.4,
  • SCYA8
  • identifiers:
  • 6355,
  • ENSG00000108700,
  • CCL8

Genome feature

Region: gene ? Length: 1968  
Location: 17:34319435-34321402 Cyto location: 17q12


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Proteins

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SNPs

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Disease

0 Diseases

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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Other

66 SN Ps

5 Cross References

17 Data Sets

13 Homologues

0 Located Features

97 Rna Seq Results