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Gene : CCL21 Homo sapiens

Name  ? C-C motif chemokine ligand 21 Cytological Location  9p13.3
Brief Description  C-C motif chemokine ligand 21
Description  This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014]
  • synonyms:
  • exodus-2,
  • Efficient Chemoattractant for Lymphocytes,
  • SLC,
  • SCYA21,
  • CKb9,
  • 6Ckine,
  • uc003zvo.5,
  • SCYA21,
  • CCL21,
  • TCA4,
  • SLC,
  • OTTHUMG00000019838,
  • chemokine (C-C motif) ligand 21,
  • secondary lymphoid tissue chemokine,
  • 6Ckine,
  • CKb9,
  • AB002409,
  • ECL,
  • HGNC:10620,
  • ECL,
  • TCA4,
  • small inducible cytokine subfamily A (Cys-Cys), member 21,
  • NM_002989,
  • beta chemokine exodus-2
  • identifiers:
  • 6366,
  • ENSG00000137077,
  • CCL21

Genome feature

Region: gene ? Length: 1132  
Location: 9:34709005-34710136 reverse strand Cyto location: 9p13.3

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0 Diseases

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7 SN Ps

5 Cross References

17 Data Sets

14 Homologues

0 Located Features

97 Rna Seq Results