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Gene : BID Homo sapiens

Name  ? BH3 interacting domain death agonist Cytological Location  22q11.21
Brief Description  BH3 interacting domain death agonist
Description  This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jan 2020]
  • synonyms:
  • OTTHUMG00000150087,
  • AF042083,
  • FP497,
  • NM_197966,
  • HGNC:1050,
  • BID,
  • uc002znd.3
  • identifiers:
  • 637,
  • ENSG00000015475,
  • BID

Genome feature

Region: gene ? Length: 40528  
Location: 22:17734138-17774665 reverse strand Cyto location: 22q11.21


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

3753 SN Ps

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results