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Gene : CX3CL1 Homo sapiens

Name  ? C-X3-C motif chemokine ligand 1 Cytological Location  16q21
Brief Description  C-X3-C motif chemokine ligand 1
Description  This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]
  • synonyms:
  • ABCD-3,
  • SCYD1,
  • fractalkine,
  • NTN,
  • NM_002996,
  • ABCD-3,
  • SCYD1,
  • OTTHUMG00000133469,
  • CXC3,
  • chemokine (C-X3-C motif) ligand 1,
  • NTN,
  • fractalkine,
  • C3Xkine,
  • CXC3C,
  • U84487,
  • neurotactin,
  • neurotactin,
  • CXC3,
  • CX3CL1,
  • NTT,
  • small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin),
  • C3Xkine,
  • HGNC:10647,
  • uc002eli.4,
  • CXC3C
  • identifiers:
  • 6376,
  • ENSG00000006210,
  • CX3CL1

Genome feature

Region: gene ? Length: 12555  
Location: 16:57372490-57385044 Cyto location: 16q21


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Disease

0 Diseases

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Other

71 SN Ps

5 Cross References

17 Data Sets

12 Homologues

0 Located Features

97 Rna Seq Results