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Gene : BIK Homo sapiens

Name  ? BCL2 interacting killer Cytological Location  22q13.2
Brief Description  BCL2 interacting killer
Description  The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011]
  • synonyms:
  • BIP1,
  • NM_001197,
  • HGNC:1051,
  • BP4,
  • BIK,
  • OTTHUMG00000150703,
  • U34584,
  • natural born killer,
  • NBK,
  • uc003bdk.3,
  • BCL2-interacting killer (apoptosis-inducing),
  • NBK
  • identifiers:
  • 638,
  • ENSG00000100290,
  • BIK

Genome feature

Region: gene ? Length: 18963  
Location: 22:43110750-43129712 Cyto location: 22q13.2

Uni Prot Comments Displayer

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Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

414 SN Ps

5 Cross References

16 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results