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Gene : CXCL12 Homo sapiens

Name  ? C-X-C motif chemokine ligand 12 Cytological Location  10q11.21
Brief Description  C-X-C motif chemokine ligand 12
Description  This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
  • synonyms:
  • PBSF,
  • SCYB12,
  • TLSF-b,
  • TLSF,
  • stromal cell-derived factor 1,
  • SDF1A,
  • SDF1,
  • PBSF,
  • IRH,
  • uc001jbi.4,
  • chemokine (C-X-C motif) ligand 12,
  • TPAR1,
  • SDF-1b,
  • L36033,
  • NM_000609,
  • OTTHUMG00000018054,
  • TPAR1,
  • TLSF-a,
  • CXCL12,
  • SDF1,
  • SDF-1a,
  • SCYB12,
  • HGNC:10672,
  • SDF1B
  • identifiers:
  • 6387,
  • ENSG00000107562,
  • CXCL12

Genome feature

Region: gene ? Length: 93010  
Location: 10:44292088-44385097 reverse strand Cyto location: 10q11.21

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



510 SN Ps

5 Cross References

18 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results