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Gene : CHP2 Homo sapiens

Name  ? calcineurin like EF-hand protein 2 Cytological Location  16p12.2
Brief Description  calcineurin like EF-hand protein 2
Description  This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520. [provided by RefSeq, Jul 2013]
  • synonyms:
  • NM_022097,
  • uc002dmb.2,
  • CHP2,
  • OTTHUMG00000131611,
  • HGNC:24927
  • identifiers:
  • 63928,
  • ENSG00000166869,
  • CHP2

Genome feature

Region: gene ? Length: 3910  
Location: 16:23755026-23758935 Cyto location: 16p12.2


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

278 SN Ps

4 Cross References

16 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results