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Gene : ERAP2 Homo sapiens

Name  ? endoplasmic reticulum aminopeptidase 2 Cytological Location  5q15
Brief Description  endoplasmic reticulum aminopeptidase 2
Description  This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]
  • synonyms:
  • leukocyte-derived arginine aminopeptidase,
  • L-RAP,
  • ERAP2,
  • L-RAP,
  • LRAP,
  • NM_022350,
  • uc003kmq.4,
  • AF191545,
  • HGNC:29499,
  • OTTHUMG00000128718,
  • LRAP
  • identifiers:
  • 64167,
  • ENSG00000164308,
  • ERAP2

Genome feature

Region: gene ? Length: 43778  
Location: 5:96875939-96919716 Cyto location: 5q15


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

35448 SN Ps

5 Cross References

16 Data Sets

16 Homologues

0 Located Features

97 Rna Seq Results