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Gene : ECSCR Homo sapiens

Name  ? endothelial cell surface expressed chemotaxis and apoptosis regulator Cytological Location  5q31.2
Brief Description  endothelial cell surface expressed chemotaxis and apoptosis regulator
Description  The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
  • synonyms:
  • ECSCR,
  • DQ462572,
  • apoptosis regulator through modulating IAP expression,
  • NM_001077693,
  • ECSM2,
  • endothelial cell-specific chemotaxis regulator,
  • ARIA,
  • HGNC:35454,
  • ECSM2,
  • ARIA,
  • endothelial cell-specific molecule 2,
  • uc032vne.2,
  • OTTHUMG00000163240
  • identifiers:
  • 641700,
  • ENSG00000249751,
  • ECSCR

Genome feature

Region: gene ? Length: 14184  
Location: 5:139448560-139462743 reverse strand Cyto location: 5q31.2


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0 Pathways

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Gene -> HPO annotation (Human Phenotype Ontology)

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

0 Pathways

119 SN Ps

5 Cross References

13 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results