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Gene : EDDM3B Homo sapiens

Name  ? epididymal protein 3B Cytological Location  14q11.2
Brief Description  epididymal protein 3B
Description  Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008]
  • synonyms:
  • FAM12B,
  • OTTHUMG00000029583,
  • HGNC:19223,
  • HE3-BETA,
  • FAM12B,
  • HE3-BETA,
  • EP3B,
  • X76386,
  • RAM2,
  • HE3B,
  • NM_022360,
  • family with sequence similarity 12, member B (epididymal),
  • EDDM3B,
  • uc001vyd.3
  • identifiers:
  • 64184,
  • ENSG00000181552,
  • EDDM3B

Genome feature

Region: gene ? Length: 2545  
Location: 14:20768404-20770948 Cyto location: 14q11.2

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

0 SN Ps

5 Cross References

14 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results