Name
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ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | Cytological Location | 5q31.3 |
Brief Description | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
Description | This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Sep 2015] |