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Gene : CLEC7A Homo sapiens

Name  ? C-type lectin domain containing 7A Cytological Location  12p13.2
Brief Description  C-type lectin domain containing 7A
Description  This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc001qxf.4,
  • BGR,
  • SCARE2,
  • C-type lectin domain family 7 member A,
  • CLEC7A,
  • CD369,
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12,
  • CD369,
  • hDectin-1,
  • CANDF4,
  • HGNC:14558,
  • NM_197954,
  • OTTHUMG00000133597,
  • C-type lectin domain family 7, member A,
  • CLECSF12,
  • SCARE2,
  • AY009090,
  • dectin-1,
  • CLECSF12,
  • DECTIN1
  • identifiers:
  • 64581,
  • ENSG00000172243,
  • CLEC7A

Genome feature

Region: gene ? Length: 13488  
Location: 12:10116777-10130264 reverse strand Cyto location: 12p13.2


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Disease

2 Diseases

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627 SNPs

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results