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Gene : EXO5 Homo sapiens

Name  ? exonuclease 5 Cytological Location  1p34.2
Brief Description  exonuclease 5
Description  The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. [provided by RefSeq, Nov 2016]
  • synonyms:
  • FLJ21144,
  • DEM1,
  • OTTHUMG00000007305,
  • C1orf176,
  • defects in morphology 1 homolog (S. cerevisiae),
  • AK024797,
  • HGNC:26115,
  • Exo V,
  • uc001cfp.4,
  • DEM1,
  • EXO5,
  • chromosome 1 open reading frame 176,
  • hExo5,
  • C1orf176,
  • NM_022774
  • identifiers:
  • 64789,
  • ENSG00000164002,
  • EXO5

Genome feature

Region: gene ? Length: 7332  
Location: 1:40508719-40516050 Cyto location: 1p34.2

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3753 SN Ps

5 Cross References

14 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results