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Gene : BMI1 Homo sapiens

Name  ? BMI1 proto-oncogene, polycomb ring finger Cytological Location  10p12.2
Brief Description  BMI1 proto-oncogene, polycomb ring finger
Description  This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015]
  • synonyms:
  • polycomb group ring finger 4,
  • FLVI2/BMI1,
  • RNF51,
  • RNF51,
  • OTTHUMG00000017807,
  • HGNC:1066,
  • PCGF4,
  • PCGF4,
  • BMI1,
  • flvi-2/bmi-1,
  • NM_005180,
  • B lymphoma Mo-MLV insertion region 1 homolog (mouse),
  • BC011652,
  • uc001irh.4
  • identifiers:
  • 648,
  • ENSG00000168283,
  • BMI1

Genome feature

Region: gene ? Length: 10386  
Location: 10:22321099-22331484 Cyto location: 10p12.2

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0 Diseases

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64 SNPs

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results