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Gene : BMP3 Homo sapiens

Name  ? bone morphogenetic protein 3 Cytological Location  4q21.21
Brief Description  bone morphogenetic protein 3
Description  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016]
  • synonyms:
  • osteogenin,
  • BMP3,
  • bone morphogenetic protein 3 (osteogenic),
  • OTTHUMG00000130292,
  • BMP-3A,
  • HGNC:1070,
  • uc003hmg.4,
  • M22491,
  • NM_001201
  • identifiers:
  • 651,
  • ENSG00000152785,
  • BMP3

Genome feature

Region: gene ? Length: 26925  
Location: 4:81030708-81057632 Cyto location: 4q21.21

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

550 SN Ps

5 Cross References

16 Data Sets

40 Homologues

0 Located Features

97 Rna Seq Results