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Gene : BMP5 Homo sapiens

Name  ? bone morphogenetic protein 5 Cytological Location  6p12.1
Brief Description  bone morphogenetic protein 5
Description  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016]
  • synonyms:
  • BMP5,
  • NM_001329754,
  • OTTHUMG00000014903,
  • uc003pcq.4,
  • HGNC:1072
  • identifiers:
  • 653,
  • ENSG00000112175,
  • BMP5

Genome feature

Region: gene ? Length: 121938  
Location: 6:55753653-55875590 reverse strand Cyto location: 6p12.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

267 SN Ps

5 Cross References

16 Data Sets

37 Homologues

0 Located Features

97 Rna Seq Results