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Gene : BMP6 Homo sapiens

Name  ? bone morphogenetic protein 6 Cytological Location  6p24.3
Brief Description  bone morphogenetic protein 6
Description  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]
  • synonyms:
  • VGR,
  • VGR1,
  • vegetal related growth factor (TGFB-related),
  • VGR,
  • OTTHUMG00000014217,
  • uc003mxu.5,
  • NM_001718,
  • VGR1,
  • HGNC:1073,
  • AF083030,
  • BMP6
  • identifiers:
  • 654,
  • ENSG00000153162,
  • BMP6

Genome feature

Region: gene ? Length: 155630  
Location: 6:7726099-7881728 Cyto location: 6p24.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

222 SN Ps

5 Cross References

17 Data Sets

37 Homologues

0 Located Features

97 Rna Seq Results