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Gene : BMP7 Homo sapiens

Name  ? bone morphogenetic protein 7 Cytological Location  20q13.31
Brief Description  bone morphogenetic protein 7
Description  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]
  • synonyms:
  • uc010gip.2,
  • HGNC:1074,
  • OP-1,
  • OTTHUMG00000032812,
  • BMP7,
  • OP-1,
  • NM_001719,
  • osteogenic protein 1
  • identifiers:
  • 655,
  • ENSG00000101144,
  • BMP7

Genome feature

Region: gene ? Length: 97889  
Location: 20:57168753-57266641 reverse strand Cyto location: 20q13.31

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

16 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results