help  | about  | cite  | software

Gene : BMPR1A Homo sapiens

Name  ? bone morphogenetic protein receptor type 1A Cytological Location  10q23.2
Brief Description  bone morphogenetic protein receptor type 1A
Description  The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]
  • synonyms:
  • ACVRLK3,
  • 10q23del,
  • OTTHUMG00000018657,
  • bone morphogenetic protein receptor, type IA,
  • BMPR1A,
  • CD292,
  • HGNC:1076,
  • NM_004329,
  • CD292,
  • SKR5,
  • ALK3,
  • uc001kdy.4,
  • ALK3,
  • BC028383,
  • ACVRLK3
  • identifiers:
  • 657,
  • ENSG00000107779,
  • BMPR1A

Genome feature

Region: gene ? Length: 172184  
Location: 10:86755786-86927969 Cyto location: 10q23.2


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3756 SN Ps

5 Cross References

20 Data Sets

17 Homologues

2 Located Features

97 Rna Seq Results