help  | about  | cite  | software

Gene : BMPR1A Homo sapiens

Name  ? bone morphogenetic protein receptor type 1A Cytological Location  10q23.2
Brief Description  bone morphogenetic protein receptor type 1A
Description  The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]
  • synonyms:
  • bone morphogenetic protein receptor, type IA,
  • 10q23del,
  • ALK3,
  • BMPR1A,
  • HGNC:1076,
  • SKR5,
  • OTTHUMG00000018657,
  • ALK3,
  • ACVRLK3,
  • ACVRLK3,
  • CD292,
  • uc001kdy.4,
  • CD292,
  • BC028383,
  • NM_004329
  • identifiers:
  • 657,
  • ENSG00000107779,
  • BMPR1A

Genome feature

Region: gene ? Length: 172184  
Location: 10:86755786-86927969 Cyto location: 10q23.2

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

19 Data Sets

6 Homologues

2 Located Features

97 Rna Seq Results