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Gene : ELOA Homo sapiens

Name  ? elongin A Cytological Location  1p36.11
Brief Description  elongin A
Description  This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq, Jul 2008]
  • synonyms:
  • TCEB3,
  • SIII,
  • TCEB3A,
  • SIII,
  • uc057dgm.1,
  • OTTHUMG00000002957,
  • TCEB3A,
  • NM_003198,
  • ELOA,
  • transcription elongation factor B subunit 3,
  • transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A),
  • SIII p110,
  • L47345,
  • HGNC:11620,
  • TCEB3
  • identifiers:
  • 6924,
  • ENSG00000011007,
  • ELOA

Genome feature

Region: gene ? Length: 18694  
Location: 1:23743366-23762059 Cyto location: 1p36.11

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664 SN Ps

5 Cross References

16 Data Sets

6 Homologues

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97 Rna Seq Results