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Gene : BUB1 Homo sapiens

Name  ? BUB1 mitotic checkpoint serine/threonine kinase Cytological Location  2q13
Brief Description  BUB1 mitotic checkpoint serine/threonine kinase
Description  This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • synonyms:
  • uc002tgc.5,
  • BUB1,
  • NM_004336,
  • BUB1L,
  • BUB1A,
  • hBUB1,
  • AF046078,
  • OTTHUMG00000153638,
  • HGNC:1148,
  • hBUB1,
  • BUB1A,
  • budding uninhibited by benzimidazoles 1 (yeast homolog),
  • budding uninhibited by benzimidazoles 1 homolog (yeast),
  • BUB1L
  • identifiers:
  • 699,
  • ENSG00000169679,
  • BUB1

Genome feature

Region: gene ? Length: 40536  
Location: 2:110637528-110678063 reverse strand Cyto location: 2q13

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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19 SN Ps

5 Cross References

18 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results