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Gene : GGTLC3 Homo sapiens

Name  ? gamma-glutamyltransferase light chain family member 3 Cytological Location  22q11.21
Brief Description  gamma-glutamyltransferase light chain family member 3
Description  Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC3, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]
  • synonyms:
  • gamma-glutamyltransferase light chain 3,
  • GGTLC3,
  • HGNC:33426,
  • uc062biv.1,
  • NM_001355479,
  • OTTHUMG00000188352,
  • GGT,
  • L10397
  • identifiers:
  • 728226,
  • ENSG00000274252,
  • GGTLC3

Genome feature

Region: gene ? Length: 1831  
Location: 22:18516335-18518165 reverse strand Cyto location: 22q11.21

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

14 SN Ps

5 Cross References

11 Data Sets

0 Homologues

0 Located Features

97 Rna Seq Results