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Gene : CCR2 Homo sapiens

Name  ? C-C motif chemokine receptor 2 Cytological Location  3p21.31
Brief Description  C-C motif chemokine receptor 2
Description  The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
  • synonyms:
  • NM_000647,
  • CKR2,
  • CCR-2,
  • chemokine (C-C motif) receptor 2,
  • HGNC:1603,
  • CCR2B,
  • CCR2,
  • CC-CKR-2,
  • FLJ78302,
  • CMKBR2,
  • OTTHUMG00000156466,
  • MCP-1-R,
  • MCP-1-R,
  • CKR2A,
  • CD192,
  • CKR2,
  • uc003cpn.5,
  • CD192,
  • CCR2A,
  • CKR2B,
  • CMKBR2,
  • CC-CKR-2
  • identifiers:
  • 729230,
  • ENSG00000121807,
  • CCR2

Genome feature

Region: gene ? Length: 7197  
Location: 3:46353744-46360940 Cyto location: 3p21.31

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

18 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results