help  | about  | cite  | software

Gene : UBTF Homo sapiens

Name  ? upstream binding transcription factor Cytological Location  17q21.31
Brief Description  upstream binding transcription factor
description  This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]
  • synonyms:
  • UBF1,
  • UBF,
  • NOR-90,
  • NM_014233,
  • UBF-1,
  • UBF1,
  • upstream binding transcription factor, RNA polymerase I,
  • BC042297,
  • OTTHUMG00000167585,
  • NOR-90,
  • UBF2,
  • UBF2,
  • UBTF,
  • HGNC:12511,
  • uc010czt.3,
  • UBF
  • identifiers:
  • 7343,
  • ENSG00000108312,
  • UBTF

Genome feature

Region: gene ? Length: 16269  
Location: 17:44205036-44221304 reverse strand Cyto location: 17q21.31

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



80 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results