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Gene : EZR Homo sapiens

Name  ? ezrin Cytological Location  6q25.3
Brief Description  ezrin
Description  The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:12691,
  • CVIL,
  • OTTHUMG00000015917,
  • AF187552,
  • VIL2,
  • NM_003379,
  • cytovillin 2,
  • CVL,
  • HEL-S-105,
  • villin 2 (ezrin),
  • EZR,
  • VIL2,
  • uc003qru.5
  • identifiers:
  • 7430,
  • ENSG00000092820,
  • EZR

Genome feature

Region: gene ? Length: 53625  
Location: 6:158765744-158819368 reverse strand Cyto location: 6q25.3


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

3753 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results