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Gene : DAP3 Homo sapiens

Name  ? death associated protein 3 Cytological Location  1q22
Brief Description  death associated protein 3
Description  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010]
  • synonyms:
  • MRPS29,
  • OTTHUMG00000035439,
  • MGC126059,
  • DAP3,
  • HGNC:2673,
  • mitochondrial 28S ribosomal protein S29,
  • X83544,
  • bMRP-10,
  • DKFZp686G12159,
  • DAP-3,
  • MGC126058,
  • bMRP-10,
  • MRP-S29,
  • NM_004632,
  • S29mt,
  • DAP-3,
  • MRP-S29,
  • MRPS29,
  • uc001flr.4
  • identifiers:
  • 7818,
  • ENSG00000132676,
  • DAP3

Genome feature

Region: gene ? Length: 51109  
Location: 1:155687902-155739010 Cyto location: 1q22


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Gene -> HPO annotation (Human Phenotype Ontology)

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

3753 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results