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Gene : CXCR4 Homo sapiens

Name  ? C-X-C motif chemokine receptor 4 Cytological Location  2q22.1
Brief Description  C-X-C motif chemokine receptor 4
Description  This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NPY3R,
  • HM89,
  • LAP-3,
  • FB22,
  • CD184,
  • NPYR,
  • CD184,
  • CXCR4,
  • LESTR,
  • HGNC:2561,
  • NPY3R,
  • NPYY3R,
  • AF005058,
  • LESTR,
  • LAP3,
  • OTTHUMG00000153583,
  • HM89,
  • HSY3RR,
  • WHIM,
  • fusin,
  • D2S201E,
  • chemokine (C-X-C motif) receptor 4,
  • chemokine (C-X-C motif), receptor 4 (fusin),
  • WHIMS,
  • NPYRL,
  • HSY3RR,
  • LCR1,
  • NPYR,
  • uc002tuy.3,
  • NPYY3R,
  • NM_001008540,
  • D2S201E
  • identifiers:
  • 7852,
  • ENSG00000121966,
  • CXCR4

Genome feature

Region: gene ? Length: 3801  
Location: 2:136114349-136118149 reverse strand Cyto location: 2q22.1


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Disease

1 Diseases

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Other

390 SN Ps

5 Cross References

19 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results