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Gene : GGCT Homo sapiens

Name  ? gamma-glutamylcyclotransferase Cytological Location  7p14.3
Brief Description  gamma-glutamylcyclotransferase
Description  The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
  • synonyms:
  • Ggc,
  • GGCT,
  • GCTG,
  • GCTG,
  • C7orf24,
  • BC019243,
  • GGC,
  • CRF21,
  • uc003tba.4,
  • chromosome 7 open reading frame 24,
  • MGC3077,
  • NM_024051,
  • OTTHUMG00000128593,
  • C7orf24,
  • HGNC:21705,
  • CRF21
  • identifiers:
  • 79017,
  • ENSG00000006625,
  • GGCT

Genome feature

Region: gene ? Length: 8221  
Location: 7:30496621-30504841 reverse strand Cyto location: 7p14.3


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Disease

0 Diseases

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3753 SN Ps

5 Cross References

17 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results