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Gene : CENPM Homo sapiens

Name  ? centromere protein M Cytological Location  22q13.2
Brief Description  centromere protein M
Description  The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  • synonyms:
  • HGNC:18352,
  • OTTHUMG00000151277,
  • C22orf18,
  • MGC861,
  • PANE1,
  • CENP-M,
  • C22orf18,
  • uc003bbn.4,
  • BC000705,
  • CENPM,
  • NM_024053,
  • Pane1,
  • chromosome 22 open reading frame 18,
  • CENP-M
  • identifiers:
  • 79019,
  • ENSG00000100162,

Genome feature

Region: gene ? Length: 19418  
Location: 22:41927747-41947164 reverse strand Cyto location: 22q13.2

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3753 SN Ps

5 Cross References

16 Data Sets

3 Homologues

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97 Rna Seq Results