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Gene : CHAC1 Homo sapiens

Name  ? ChaC glutathione specific gamma-glutamylcyclotransferase 1 Cytological Location  15q15.1
Brief Description  ChaC glutathione specific gamma-glutamylcyclotransferase 1
Description  This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016]
  • synonyms:
  • BC019625,
  • NM_024111,
  • ChaC, cation transport regulator homolog 1 (E. coli),
  • gamma-GCT acting on glutathione homolog 1,
  • uc059hwj.1,
  • HGNC:28680,
  • CHAC1,
  • OTTHUMG00000130208,
  • MGC4504
  • identifiers:
  • 79094,
  • ENSG00000128965,
  • CHAC1

Genome feature

Region: gene ? Length: 14382  
Location: 15:40942137-40956518 Cyto location: 15q15.1

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0 Diseases

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349 SNPs

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results