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Gene : BIRC7 Homo sapiens

Name  ? baculoviral IAP repeat containing 7 Cytological Location  20q13.33
Brief Description  baculoviral IAP repeat containing 7
Description  This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]
  • synonyms:
  • baculoviral IAP repeat-containing 7,
  • kidney inhibitor of apoptosis protein,
  • mliap,
  • livin inhibitor-of-apoptosis,
  • AF301009,
  • uc002yej.4,
  • RNF50,
  • RNF50,
  • KIAP,
  • ML-IAP,
  • KIAP,
  • OTTHUMG00000032957,
  • MLIAP,
  • NM_139317,
  • HGNC:13702,
  • ML-IAP,
  • livin,
  • melanoma inhibitor of apoptosis protein,
  • BIRC7,
  • identifiers:
  • 79444,
  • ENSG00000101197,
  • BIRC7

Genome feature

Region: gene ? Length: 4591  
Location: 20:63235905-63240495 Cyto location: 20q13.33

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3740 SNPs

5 Cross References

14 Data Sets

4 Homologues

2 Located Features

97 Rna Seq Results