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Gene : CALD1 Homo sapiens

Name  ? caldesmon 1 Cytological Location  7q33
Brief Description  caldesmon 1
Description  This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CDM,
  • L-CAD,
  • CDM,
  • LCAD,
  • H-CAD,
  • NAG22,
  • HCAD,
  • CALD1,
  • NM_033138,
  • uc003vrz.4,
  • HGNC:1441,
  • H-CAD,
  • OTTHUMG00000155407,
  • M64110,
  • L-CAD
  • identifiers:
  • 800,
  • ENSG00000122786,
  • CALD1

Genome feature

Region: gene ? Length: 191101  
Location: 7:134779629-134970729 Cyto location: 7q33


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Disease

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605 SN Ps

5 Cross References

18 Data Sets

4 Homologues

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97 Rna Seq Results