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Gene : FBXL18 Homo sapiens

Name  ? F-box and leucine rich repeat protein 18 Cytological Location  7p22.1
Brief Description  F-box and leucine rich repeat protein 18
Description  The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. [provided by RefSeq, Mar 2016]
  • synonyms:
  • HGNC:21874,
  • FLJ11467,
  • FBXL18,
  • Fbl18,
  • Fbl18,
  • uc003son.5,
  • OTTHUMG00000151832,
  • NM_024963,
  • AK057042
  • identifiers:
  • 80028,
  • ENSG00000155034,
  • FBXL18

Genome feature

Region: gene ? Length: 59385  
Location: 7:5454425-5513809 reverse strand Cyto location: 7p22.1

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

998 SN Ps

5 Cross References

16 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results