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Gene : CD276 Homo sapiens

Name  ? CD276 molecule Cytological Location  15q24.1
Brief Description  CD276 molecule
Description  The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  • synonyms:
  • B7-H3,
  • NM_025240,
  • 4Ig-B7-H3,
  • CD276,
  • B7H3,
  • OTTHUMG00000137585,
  • B7-H3,
  • AF302102,
  • B7H3,
  • HGNC:19137,
  • B7RP-2,
  • CD276 antigen,
  • B7RP-2,
  • uc002avv.2
  • identifiers:
  • 80381,
  • ENSG00000103855,
  • CD276

Genome feature

Region: gene ? Length: 30553  
Location: 15:73683966-73714518 Cyto location: 15q24.1

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Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

693 SNPs

5 Cross References

16 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results