help  | about  | cite  | software

Gene : ITIH5 Homo sapiens

Name  ? inter-alpha-trypsin inhibitor heavy chain 5 Cytological Location  10p14
Brief Description  inter-alpha-trypsin inhibitor heavy chain 5
Description  This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
  • synonyms:
  • HGNC:21449,
  • ITI-HC5,
  • MGC10848,
  • ITIH5,
  • PP14776,
  • inter-alpha-trypsin inhibitor heavy chain family, member 5,
  • OTTHUMG00000017635,
  • NM_030569,
  • inter-alpha (globulin) inhibitor H5,
  • uc031vwl.2
  • identifiers:
  • 80760,
  • ENSG00000123243,
  • ITIH5

Genome feature

Region: gene ? Length: 107729  
Location: 10:7559270-7666998 reverse strand Cyto location: 10p14


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

893 SN Ps

5 Cross References

17 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results