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Gene : CALR Homo sapiens

Name  ? calreticulin Cytological Location  19p13.13
Brief Description  calreticulin
Description  Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]
  • synonyms:
  • SSA,
  • CALR,
  • M84739,
  • uc002mvu.3,
  • Sicca syndrome antigen A (autoantigen Ro; calreticulin),
  • cC1qR,
  • SSA,
  • FLJ26680,
  • RO,
  • cC1qR,
  • CRT,
  • autoantigen Ro,
  • OTTHUMG00000180574,
  • HEL-S-99n,
  • RO,
  • HGNC:1455,
  • NM_004343,
  • CRT
  • identifiers:
  • 811,
  • ENSG00000179218,
  • CALR

Genome feature

Region: gene ? Length: 5881  
Location: 19:12938609-12944489 Cyto location: 19p13.13

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



929 SNPs

5 Cross References

19 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results