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Gene : CAMK2A Homo sapiens

Name  ? calcium/calmodulin dependent protein kinase II alpha Cytological Location  5q32
Brief Description  calcium/calmodulin dependent protein kinase II alpha
Description  The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]
  • synonyms:
  • OTTHUMG00000134281,
  • CaM kinase II alpha subunit,
  • MRT63,
  • CAMKA,
  • CAMKA,
  • CaMKIINalpha,
  • calcium/calmodulin-dependent protein kinase II alpha-B subunit,
  • CaM-kinase II alpha chain,
  • CaMK-II alpha subunit,
  • CaMKIIalpha,
  • calcium/calmodulin-dependent protein kinase type II alpha chain,
  • HGNC:1460,
  • NM_015981,
  • MRD53,
  • AB023185,
  • uc003lru.3,
  • calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha,
  • CaMKII╬▒,
  • KIAA0968,
  • CAMK2A,
  • CaMKIINalpha
  • identifiers:
  • 815,
  • ENSG00000070808,
  • CAMK2A

Genome feature

Region: gene ? Length: 70640  
Location: 5:150219491-150290130 reverse strand Cyto location: 5q32


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2 Diseases

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0 Pathways

302 SNPs

5 Cross References

19 Data Sets

5 Homologues

1 Located Features

97 Rna Seq Results