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Gene : CANX Homo sapiens

Name  ? calnexin Cytological Location  5q35.3
Brief Description  calnexin
Description  This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018]
  • synonyms:
  • IP90,
  • IP90,
  • CNX,
  • P90,
  • L18887,
  • major histocompatibility complex class I antigen-binding protein p88,
  • P90,
  • uc003mkl.4,
  • HGNC:1473,
  • CANX,
  • OTTHUMG00000130910,
  • NM_001024649,
  • CNX
  • identifiers:
  • 821,
  • ENSG00000127022,
  • CANX

Genome feature

Region: gene ? Length: 52996  
Location: 5:179678646-179731641 Cyto location: 5q35.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

3756 SN Ps

5 Cross References

17 Data Sets

11 Homologues

0 Located Features

97 Rna Seq Results