help  | about  | cite  | software

Gene : EOMES Homo sapiens

Name  ? eomesodermin Cytological Location  3p24.1
Brief Description  eomesodermin
Description  This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
  • synonyms:
  • OTTHUMG00000130570,
  • eomesodermin (Xenopus laevis) homolog,
  • TBR2,
  • TBR2,
  • HGNC:3372,
  • BC025363,
  • uc003cdx.5,
  • T-box brain2,
  • EOMES,
  • NM_005442
  • identifiers:
  • 8320,
  • ENSG00000163508,
  • EOMES

Genome feature

Region: gene ? Length: 6767  
Location: 3:27715949-27722715 reverse strand Cyto location: 3p24.1


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

133 SN Ps

5 Cross References

15 Data Sets

18 Homologues

0 Located Features

97 Rna Seq Results