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Gene : EOMES Homo sapiens

Name  ? eomesodermin Cytological Location  3p24.1
Brief Description  eomesodermin
Description  This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
  • synonyms:
  • OTTHUMG00000130570,
  • eomesodermin (Xenopus laevis) homolog,
  • TBR2,
  • TBR2,
  • HGNC:3372,
  • BC025363,
  • uc003cdx.5,
  • T-box brain2,
  • EOMES,
  • NM_005442
  • identifiers:
  • 8320,
  • ENSG00000163508,

Genome feature

Region: gene ? Length: 6767  
Location: 3:27715949-27722715 reverse strand Cyto location: 3p24.1

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

133 SN Ps

5 Cross References

15 Data Sets

18 Homologues

0 Located Features

97 Rna Seq Results