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Gene : CARS1 Homo sapiens

Name  ? cysteinyl-tRNA synthetase 1 Cytological Location  11p15.4
Brief Description  cysteinyl-tRNA synthetase 1
Description  This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]
  • synonyms:
  • CARS1,
  • NM_001751,
  • CARS,
  • CYSRS,
  • CARS,
  • cysteine tRNA ligase 1, cytoplasmic,
  • uc001lxh.4,
  • HGNC:1493,
  • AF288207,
  • MGC:11246,
  • OTTHUMG00000010927,
  • cysteinyl-tRNA synthetase
  • identifiers:
  • 833,
  • ENSG00000110619,
  • CARS1

Genome feature

Region: gene ? Length: 56495  
Location: 11:3000929-3057423 reverse strand Cyto location: 11p15.4

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0 Diseases

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3753 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results