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Gene : H2BC8 Homo sapiens

Name  ? H2B clustered histone 8 Cytological Location  6p22.2
Brief Description  H2B clustered histone 8
Description  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
  • synonyms:
  • H2B histone family, member A,
  • HIST1H2BG,
  • H2B.1A,
  • M60750,
  • H2BC6,
  • H2BC8,
  • H2B.1A,
  • H2BFA,
  • HIST1H2BG,
  • H2B/a,
  • NM_003518,
  • uc003ngz.5,
  • H2BC10,
  • H2B/a,
  • H2BC4,
  • H2BFA,
  • histone cluster 1 H2B family member g,
  • HGNC:4746,
  • histone cluster 1, H2bg,
  • histone 1, H2bg,
  • H2BC7,
  • OTTHUMG00000014446,
  • dJ221C16.8
  • identifiers:
  • 8339,
  • ENSG00000273802,
  • H2BC8

Genome feature

Region: gene ? Length: 489  
Location: 6:26216200-26216688 reverse strand Cyto location: 6p22.2

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95 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



95 Pathways

175 SN Ps

4 Cross References

14 Data Sets

17 Homologues

0 Located Features

97 Rna Seq Results